A 65-year-old male is seen in rheumatology clinic.
A 65-year-old male is seen in rheumatology clinic. He was referred from the respiratory team as he has developed widespread joint pains and purpura to the lower limbs.
He has a past medical history of asthma, diagnosed 10 years ago.
Blood results are as follows:
| Admission | 12 m previously | Normal range | |
|---|---|---|---|
| Hb | 130 | 146 | (135-170) |
| WCC | 9.7 | 8.3 | (3.5-11.0) |
| Plt | 420 | 350 | (140-400) |
| Neut | 8.3 | 7.1 | (1.7-7.5) |
| Eosinophils | 0.12 | 0.14 | (0.0-0.5) |
| Basophils | 0.07 | 0.08 | (0.0-0.1) |
| ESR | 35 | 15 | |
| Urea | 7.2 | 5.4 | (2.9-8.2) |
| Creatinine | 162 | 85 | (66-112) |
| eGFR | 30 | >90 | |
| CRP | 12 | 5 | (0-5) |
Chest X-ray: diffuse pulmonary infiltrates bilaterally
Renal biopsy: linear IgG deposition along glomerular capillaries
What is the most likely diagnosis?
Select the SINGLE most appropriate option from the list below. Select ONE option only.
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