20th June 2024

A 66-year-old gentleman is admitted to hospital with 3 weeks of fevers

A 66-year-old gentleman is admitted to hospital with 3 weeks of fevers, malaise and anorexia. He is pyrexial and blood pressure is 124/63 mmHg, pulse is 108/min, respiratory rate is 20/min, SpO2 95% on room air. There is a new pan-systolic murmur over the left sternal edge. He has no past medical history and is not taking any new medication. Blood tests and blood cultures are taken. An empirical diagnosis of infective endocarditis is made. He is awaiting an echocardiogram.

What is the appropriate initial antibiotic regime for this patient?

Select the SINGLE most appropriate option from the list below. Select ONE option only.