20th February 2025

A 73-year-old man is referred to the respiratory clinic due to increasing shortness of breath and cough for the last year.

A 73-year-old man is referred to the respiratory clinic due to increasing shortness of breath and cough for the last year. His past medical history includes ischaemic heart disease, atrial fibrillation, non-Hodgkin’s lymphoma and osteoarthritis. He has forgotten to bring his medication list with him. He is allergic to penicillin. 

There are fine crackles bilaterally on examination of the chest.

His high-resolution CT scan shows triangular-shaped, patchy ground glass opacities peripherally with some air bronchograms.

Which medication is most likely to have caused the pattern of fibrosis observed?

Select the SINGLE most appropriate option from the list below. Select ONE option only.