21st February 2025

A 78-year-old man presents with a 5-day history of fevers and a productive cough.

A 78-year-old man presents with a 5-day history of fevers and a productive cough. Past medical history includes hypertension and type II diabetes, for which he takes amlodipine, losartan and metformin. He is a lifelong non-smoker and drinks around 5-6 units of alcohol per week. A chest X-ray demonstrates a right lower zone pneumonia which is treated successfully with antibiotics. On a follow up X-ray a month later, resolution of consolidation reveals a suspicious right lower zone lesion. A CT confirms a 3 cm peripheral lung mass which is subsequently biopsied. 

The biopsy is most likely to reveal which of the following pathologies?

Select the SINGLE most appropriate option from the list below. Select ONE option only.