21st June 2024

A patient attends your TB clinic for monitoring of their symptoms and biochemistry results

A patient attends your TB clinic for monitoring of their symptoms and biochemistry results while on first-line anti-tuberculous therapy for a diagnosis of pulmonary TB. On close questioning, they report paraesthesia and a burning sensation in their feet. On physical examination, impaired fine touch discrimination is detected on both feet in a “stocking” distribution, up to the level of the malleoli. Which of the following first-line anti-tuberculous agents is most likely to have caused this complication?

Select the SINGLE most appropriate option from the list below. Select ONE option only.