26th May 2025

A patient is referred to your specialist centre. He presents with sweating, palpitations, blurred vision and headaches.

A patient is referred to your specialist centre. He presents with sweating, palpitations, blurred vision and headaches.  CT with contrast finds an adrenal mass with multiple pancreatic and renal cysts. He goes on to have surgery to remove the tumour and histology confirms the suspected phaeochromocytoma. 

What is the most likely underlying genetic mutation?

Select the SINGLE most appropriate option from the list below. Select ONE option only.