14th July 2026

An 89-year-old woman with Fitzpatrick type I skin presents with a single 12mm lesion on her forearm.

An 89-year-old woman with Fitzpatrick type I skin presents with a single 12mm lesion on her forearm. No other lesions are noted. Histology shows a moderately differentiated SCC, with a depth of 2.5mm arising within Bowen’s disease. Her medication history includes ramipril, simvastatin and Adcal D3. Which of the following is most likely associated with a greater risk of recurrence?

Select the SINGLE most likely answer from the list below. Select ONE option only.