19th May 2025

Mr Ellis is a 39-year-old patient who has been found to have deranged liver function tests since commencing tuberculosis treatment with isoniazid.

Mr Ellis is a 39-year-old patient who has been found to have deranged liver function tests since commencing tuberculosis treatment with isoniazid. Which of the following is in keeping with the diagnostic criteria for hepatocellular drug-induced liver injury (DILI)? 

Key: ALT = alanine aminotransferase, AST = aspartate aminotransferase, ALP = alkaline phosphatase, ULN = upper limit of normal. 

Select the SINGLE most appropriate option from the list below. Select ONE option only.