24th June 2026

You are a cardiology SHO in a district general hospital.

You are a cardiology SHO in a district general hospital. You are asked by the pharmacist to review a patient’s antibiotics. The patient has a diagnosis of methicillin-resistant staphylococcus aureus infective endocarditis affecting the aortic valve. The isolated organism is sensitive to all other antibiotics. They had a bioprosthetic aortic valve replacement 2 years ago. They are currently on vancomycin and rifampicin. They have no known allergies. 

What is the best option with regards to managing their antibiotic therapy? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.