19th May 2025

You are asked to review a 69-year-old female patient whose blood tests show a decline in glomerular filtration rate over the past 7 days and increase in serum creatinine by 350% compared with her baseline.

You are asked to review a 69-year-old female patient whose blood tests show a decline in glomerular filtration rate over the past 7 days and increase in serum creatinine by 350% compared with her baseline. This was presumed secondary to reduced oral intake and she was prescribed intravenous fluids, however no improvement in her renal function was seen. On reviewing her drug chart you note that she has recently been prescribed acetazolamide since attending an ophthalmology clinic appointment. Which of the following options is most likely to be the cause of her impaired renal function?

Select the SINGLE most appropriate option from the list below. Select ONE option only.