24th August 2020

A 12-year-old boy is seen in the haematology clinic

A 12-year-old boy is seen in the haematology clinic. He is currently being treated with chemotherapy for an acute form of leukaemia which presents with a large number of blast cells on the blood film. Your consultant tells you that the patient has his BCR-ABL1 levels monitored, also known as the Philadelphia chromosome levels.

Which of the following genetic pairs correctly identifies the Philadelphia chromosome?

Select the SINGLE most appropriate option from the list below. Select ONE option only.