1st September 2020

A 19-year-old student presented to the A&E with 2 days of non-blanching, widespread maculopapular rash

A 19-year-old student presented to the A&E with 2 days of non-blanching, widespread maculopapular rash on her trunk, arms and face. The rash started on her trunk and forearm but spread towards her face this morning. She denied any symptoms of itching, bleeding, bruising and difficulty breathing. On further questioning, she mentioned that she was prescribed amoxicillin by her GP for her sore throat. Otherwise she denied any other symptoms such as diarrhoea, nausea, vomiting, chesty cough and pain on urination. She denied any recent travelling history and has never had sexual intercourse. Vaccination history is up to date. She denied having any drug allergies in the past. On physical examination, you also noticed an enlarged spleen and cervical lymphadenopathy. 

A throat swab ordered by the GP came back negative for any microorganisms. 

What is the most likely underlying cause of the rash? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.