25th August 2020

A 32-year-old lady presented to the GP with 4 months of unintentional weight loss, palpitations, oligomenorrhoea, restlessness, dysphagia and heat intolerance

A 32-year-old lady presented to the GP with 4 months of unintentional weight loss, palpitations, oligomenorrhoea, restlessness, dysphagia and heat intolerance. On further questioning, she denies having symptoms of headache, dizziness, abdominal cramps, night sweats, difficulty breathing or chest pain. She does not have any significant past medical history or family history. She denied any smoking history. She drinks 4 pints of beer a week. On examination, you have noticed a diffuse swelling of the neck, fine tremor, tachycardia and onycholysis. 

A diagnosis of Graves’ disease is suspected by the GP. Which of the following antibodies would be typically raised in Graves’ disease?

Select ONE option.