28th August 2020

A 42-year-old woman presents to her general practitioner (GP) with fatigue

A 42-year-old woman presents to her general practitioner (GP) with fatigue, which she mentions has been persisting for several months. Additionally, she reports excessive thirst and frequent urination. Over the past two months, she has lost nearly 14 pounds in weight. The GP conducts some general blood tests which yield the following results:

• Random plasma glucose 12.5mmol/L (3.9 – 7.8 mmol/L)
• Sodium 136mmol/L (135 – 145 mmol/L)
• Potassium 3.9mmol/L (3.5 – 5.0 mmol/L)
• Bicarbonate 26mmol/L (22 – 29 mmol/L)
• Creatinine 48mmol/L (45 – 84 mmol/L)
• Urea 5.2mmol/L (2.5 – 7.1 mmol/L)
• Serum osmolality 287mOsmol/kg (275 – 295 mOsmol/kg).

For the patient described above, please select the SINGLE most likely diagnosis from the list below. Select ONE option only.