2nd September 2020

A 45-year-old man presents with a 3-month history of rhinitis and pain in the nose, as well as itching eyes

A 45-year-old man presents with a 3-month history of rhinitis and pain in the nose, as well as itching eyes. On examination, he has several nasal mucosal ulcers and a saddle-shaped deformity of the nasal bridge, as well as a bilateral conjunctivitis. 

Given the likely diagnosis, which antibody is the most likely to be positive?

Select the SINGLE most appropriate option from the list below. Select ONE option only.