26th August 2020

A 48-year-old woman is brought in by ambulance after a fall early in the morning

A 48-year-old woman is brought in by ambulance after a fall early in the morning. She states that her gait has been unsteady over a period of time and is gradually worsening. Her daughter noticed that the patient’s cognitive function has started to decline and she tends to lose her temper easily. At times she can be aggressive. On examination, the patient presents with jerky involuntary movements, saccadic eye movements, and clonus is present. Extensor plantar reflex is positive. 

What is the most likely cause of this clinical picture? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.