26th August 2020

A 50-year-old gentleman presents with a few months’ history of incoordination and unsteady gait

A 50-year-old gentleman presents with a few months’ history of incoordination and unsteady gait. His condition further deteriorates into sporadic jerky involuntary movements accompanied by gradual decline of cognitive function. He admitted that his mood has been low for a while and he thinks that it is exacerbated by his uncontrolled movements. His father was diagnosed with Huntington’s disease when he was around his late 40s. Otherwise, he does not have any significant past medical history. 

What is the most appropriate investigation to confirm the diagnosis?    

Select the SINGLE most appropriate option from the list below. Select ONE option only.