23rd January 2024

A 73-year-old male is admitted to hospital for severe diabetic foot infection

A 73-year-old male is admitted to hospital for severe diabetic foot infection and is treated with clindamycin. During his stay, he develops watery diarrhoea with 7 stools a day. He has no significant medical history. On examination, he is warm to touch and demonstrates tenderness upon palpation of the lower abdomen. Salient observations include a temperature of 38.6oC. A stool test is positive for toxin B and a blood test reveals a white cell count (WCC) of 16 x 10⁹/L.

Which of the following is the most appropriate first-line management?

Select the SINGLE most appropriate option from the list below. Select ONE option only.