28th August 2020

A woman is seen by her general practitioner with tiredness and lethargy

A woman is seen by her general practitioner with tiredness and lethargy. She is otherwise fit and well. As a result, some blood tests are sent off to determine if there is an organic cause for her symptoms. The results are as follows: haemoglobin 12.3g/dl, white cell count 6.2×109/L, sodium 141mmol/L, potassium 4.2mmol/L, bicarbonate 23mmol/L, urea 4mmol/L, creatinine 52mmol/L, fasting serum glucose 6.1mmol/L, triglycerides 1.2mmol/L, and high-density lipoprotein 1.6mmol/L. She goes on to have an oral glucose tolerance test (OGTT) that comes back as 8.9mmol/L after 2 hours. 

Which of the following is the most likely cause? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.