16th September 2020

Mr Flint is a 66-year-old gentleman who has recently been diagnosed with Prostate Cancer

Mr Flint is a 66-year-old gentleman who has recently been diagnosed with Prostate Cancer. Following discussion with the team he has decided to begin androgen-deprivation-therapy and he is being started on a drug called “Goserelin”. This drug is a synthetic analogue of GnRH. 

By what mechanism will a GnRH Analogue lead to a reduction of sex hormones to castration levels?

Select the SINGLE most appropriate option from the list below. Select ONE option only.