1st April 2022

A 23-year-old female presents to A&E with a 4 day history of a Crohn’s exacerbation

A 23-year-old female presents to A&E with a 4 day history of a Crohn’s exacerbation. She is opening her bowels up to 12 times a day despite taking loperimide. She has significant abdominal pain and is severely dehydrated. She has a fever of 38.3⁰C.  She is not currently on any medications, and has not had a Crohns flare for the past years. IV fluids are started.

Which initial medication should be started to treat the acute exacerbation?

Which is the SINGLE most appropriate option from the list below? Select ONE option only.