27th September 2021

A 34-year-old lady with clinical features of anaemia has recently undergone blood tests

A 34-year-old lady with clinical features of anaemia has recently undergone blood tests, which suggest a haemolytic element to her anaemia. The doctor, therefore, orders a blood film to be taken to evaluate her condition further. The blood film is returned, revealing schistocytes (red blood cell fragments).

In which of the following causes of haemolytic anaemia would schistocytes be MOST likely to be present? Select ONE option only.