1st April 2022

A 35-year-old man with no past medical history presents with a solid lump in the right testicle

A 35-year-old man with no past medical history presents with a solid lump in the right testicle, testicular pain and gynaecomastia for the past 2 months. The patient’s brother and uncle on his mother’s side have previously been diagnosed with testicular cancer. You suspect the patient might carry a certain gene on their X-chromosome, increasing his risk of testicular malignancy by up to 50 times.   

Select the SINGLE most appropriate gene from the list below. Select ONE option only.