1st April 2022

A 36-year-old gentleman presented to the GP practice with 6 weeks of pruritus and lethargy

A 36-year-old gentleman presented to the GP practice with 6 weeks of pruritus and lethargy. Further investigations showed positive p-ANCA result and MRCP finding of a “beads on a string” like picture. He is a known ulcerative colitis patient under the care of a gastroenterologist. Which of the following medications below would be first-line in the management of pruritus in this patient? Select ONE option only.