1st April 2022

A 50-year-old male presents with a 3-month history of joint and muscle pain

A 50-year-old male presents with a 3-month history of joint and muscle pain. He also complains of exertional breathlessness that has become more noticeable over the past 2 weeks. On examination, there are bilateral coarse crackles. Subsequent investigations confirm a diagnosis of anti-synthetase syndrome.  

Which of the following underlying conditions is the patient most likely to have?

Select the SINGLE most appropriate option from the list below. Select ONE option only.