23rd September 2021

A 65-year-old male presents to his GP with spontaneous, bloody nipple discharge

A 65-year-old male presents to his GP with spontaneous, bloody nipple discharge from his right breast. This had been ongoing for a few weeks, though he reports no pain associated with it. His past medical history includes liver cirrhosis and prostate cancer, for which he takes oestrogen therapy after unsuccessful trials of alternative hormonal treatments. There is a significant family history of both prostate and breast cancer. On examination, there are no lumps or skin changes on either breast, which both appear normal. His body-mass index (BMI) is 35.

Which of the following are considered the most appropriate first-line investigation(s)?

Select the SINGLE most appropriate option from the list below. Select ONE option only.