1st April 2022

A 70-year-old man presents to the dermatology outpatients clinic regarding a lesion on his nose

A 70-year-old man presents to the dermatology outpatients clinic regarding a lesion on his nose that has been slowly growing for the past 8 months. A skin biopsy is taken and the tissue is analysed under haematoxylin and eosin stain. The lesion is histopathologically described to have positive cytokeratin staining with BerEP4 expression. 

What is the most likely diagnosis of the skin lesion?

Select the SINGLE most appropriate option from the list below. Select ONE option only.