1st April 2022

A 79-year-old man attends a cardiology appointment

A 79-year-old man attends a cardiology appointment. He was diagnosed with heart failure, with a reduced ejection fracture on echocardiogram, two years ago. His past medical history includes hypertension and two previous MIs. His current medications to manage his heart failure include ramipril, amlodipine, atorvastatin, bisoprolol and furosemide. The patient reports he remains breathless on minimal exertion and often wakes up during the night feeling breathless. He has bilateral pitting oedema to his mid-shins and says that his swollen ankles are painful and limits his mobility. The cardiologist considers adding spironolactone as further management of the patient’s condition.

Which of the following statements about a potential interaction of spironolactone with this patient’s current medication is correct? 

Select the SINGLE most appropriate option from the list below. Select ONE option only.