1st April 2022

A patient presents with fatigue and weakness

A patient presents with fatigue and weakness. This has been present for several weeks now. On further questioning, she has noticed a tingling sensation in her hands. A set of baseline blood tests are done, including full blood count, thyroid function tests, diabetic screen, and urea and electrolytes. Her haemoglobin comes back as 102g/L and mean corpuscular volume 110fl. 

What is the most common cause of this patient’s macrocytic anaemia?

Select the SINGLE most appropriate option from the list below. Select ONE option only.