29th February 2024

A 21-year-old female presents to the emergency department following an intentional paracetamol overdose approximately three hours ago.

A 21-year-old female presents to the emergency department following an intentional paracetamol overdose approximately three hours ago.

She is unsure of how many tablets she has ingested but admits she did not take all of them at once. She denies taking any other substances.

PM. Asthma. DH. Salbutamol 200 micrograms INH as required, beclomethasone dipropionate 200 micrograms INH 12-hrly. SH. University student.

On examination

Weight 63 kg

Investigations

Plasma paracetamol concentration at 6 hours is 86 mg/L

Select the most appropriate initial management option for this patient: