A 37-year-old man presents to the outpatient hepatology clinic with fatigue, abdominal pain and jaundice.
A 37-year-old man presents to the outpatient hepatology clinic with fatigue, abdominal pain and jaundice. On examination the following is noted:

A blood test is performed which reveals low serum caeruloplasmin, reduced total serum copper, and increased 24hr urinary copper excretion.
The patient is diagnosed with Wilson’s disease and starts on penicillamine.
Select one option which correctly describes an element of the monitoring required for penicillamine.
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