22nd February 2024

A 62 year old male with Chronic Obstructive Pulmonary Disease presents with a severe acute exacerbation to his local A&E department.

A 62 year old male with Chronic Obstructive Pulmonary Disease presents with a severe acute exacerbation to his local A&E department. He weighs 75kg and is 1.8m tall. It is decided to start the patient on a 6 hour aminophylline infusion. The initial dose should be 500 micrograms/kg/hour and the A&E department has aminophylline 250mg/10ml available for use.

How many ml of aminophylline 250mg/10ml is required for a 6 hour infusion?