A 68 year old man is admitted to hospital with a week-long history of fever and leg pain.
A 68 year old man is admitted to hospital with a week-long history of fever and leg pain. On examination, his right leg appears red and swollen and is warm and tender upon touch. His vitals are as follows: Temp 38.2, HR 114, RR 29, BP 90/85 and sats 99% on RA.

What is the single most appropriate management?
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